Cell free dna diagnostic testing standards
作者： Joshua Babiarz , Bernhard Zimmermann
DOI:
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摘要: Embodiments of the invention include methods and compositions for producing standards noninvasive prenatal genetic diagnostics detection monitoring cancer. The can a plurality different nucleosomal DNA fragments derived from either primary cells or cell lines one more synthetic oligonucleotides. amount be varied so as to simulate naturally occurring free samples obtained blood pregnant woman cancer patients.
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