Phosphorylation-mediated regulation of signal-dependent nuclear protein transport: The “CcN motif”
作者： David A. Jans
DOI: 10.1016/S1874-592X(06)80008-9
关键词:
摘要: Publisher Summary Since the sequence responsible for subcellular localization of SV40 large tumor antigen (T-ag) has been defined, research in field nuclear protein transport largely revolved around idea a signal (NLS) being exclusively localization. NLSs have defined multitude proteins, and specific NLS-binding proteins or receptors identified. The structure function is essentially same across plant animal kingdom, with from plants, yeasts, higher mammals identical. functional plants are active targeting yeast cells; mammalian T-ag NLS able to confer on appropriate, normally cytoplasmic carrier mammalian, insect, yeast, cells.
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