Comparison of compensatory pituitary and testicular responses to hemicastration between prepubertal and mature rats.
作者： Janine L. Brown , Prabir K. Chakraborty
DOI: 10.1002/J.1939-4640.1991.TB00229.X
关键词:
摘要: Prepubertal (14 days old) and mature (10 to 12 months male rats were hemicastrated killed at selected intervals during a 12-week period compare the effect of age on acute chronic pituitary testicular responses hemicastration. Testis weight was increased (P less than 0.05) in (HC) prepubertal but not compared with intact controls. After surgery, serum follicle-stimulating hormone (FSH) concentrations elevated by hour day 2 rats, respectively, remained over control levels for 4 8 weeks, respectively. However, magnitude rise FSH following hemicastration greater animals. Pituitary 1 HC through week 4. In contrast, unaffected rats. Serum inhibin-alpha inversely related only. testosterone reduced both groups recovered within 24 hours. Neither nor luteinizing (LH) altered either group. addition, there no changes LH or receptors throughout period. receptor contents association increase testis size.(ABSTRACT TRUNCATED AT 250 WORDS)
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