THE USE OF PROSTAGLANDIN E1 ANALOGUE PESSARIES IN PATIENTS HAVING FIRST TRIMESTER INDUCED ABORTIONS
作者： R. Nakano , H. Hata , K. Sasaki , M. Yamoto
DOI: 10.1111/J.1471-0528.1980.TB04541.X
关键词:
摘要: Summary A new prostaglandin analogue, 16, 16-dimethyl-trans-Δ2-PGE1 methyl ester (16 me E1) was used for preoperative cervical dilatation in 23 pregnant women who had abortion induced socio-economical reasons the first trimester of pregnancy. A single vaginal pessary containing 1 mg 16 E1was inserted into posterior fornix at 3-hour intervals. Thirteen (56.5 per cent) patients complete abortions and two (8.7 incomplete abortions. In six (26.1 cervix dilated to least 10 mm remaining required mechanical time vacuum evacuation. Apart from mild gastrointestinal symptoms, no serious side effects were noted. It is concluded that E1, could be safely effectively before surgical early
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