Dusty Air Pollution is Associated with an Increased Risk of Allergic Diseases in Southwestern Part of Iran.

作者: Mohammad Kazzem Gheybi , Ali Movahed Movahed , Reyhaneh Dehdari , Shahram Amiri , Hassan Ali Khazaei

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摘要: Concerns have been raised about the adverse impact of dusty air pollution (DAP) on human health. The aim this study was to find association between based quality index (AQI) and risk allergic diseases in southwestern provinces Iran, with assessing cytokine profiles lymphocyte immunophenotypes. In case control 148 individuals participated. sampling done hazardous condition (AQI >300) as clean <50) control. We measured production by using ELISA method phenotypes T-lymphocytes (CD4+ CD8+), CD19+ B-lymphocytes, CD25+, CD4+ CD25+ cells FACSort flow cytometer. mean serum level IL-4 (33.4±2.9 vs 0.85± 0.65 pg/dl) IL-13 (15.1±4.4 vs. 0.12±0.7 subjects exposed ambient DAP increased significantly compared condition. Also, B-lymphocytes (12.6± 4.9 8.9±3.2%) cell count (13.6± 4.6 7.7± 3.8%) peripheral blood were controls. result our suggested that affected immune system a way might lead population.

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