Short Communication - Antifungal properties of 5-hydroxytryptamine (serotonin) against Aspergillus spp. in vitro
作者： Cornelia Lass-Flörl , Barbara Wiedauer , Astrid Mayr , Martin Kirchmair , Ilse Jenewein
关键词:
摘要: This study shows that 5-hydroxytrypatmine (5-HT, serotonin) is fungicidal towards conidia and hyphae of clinical isolates Aspergillus (A.) fumigatus, A. flavus terreus. The minimal concentrations for ranged between 14.68 to 117.5 mM 29.37 235 during 24 48 h incubation. Several serotonin receptor antagonists (5-HT2, 5-HT3) studied in vitro did not influence antifungal activity.
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