Inhibitory effect of 2″-O-glycosyl isovitexin and α-tocopherol on genotoxic glyoxal formation in a lipid peroxidation system

摘要: The inhibitory effect of 2"-O-glycosyl isovitexin (2"-O-GIV), isolated from young barley leaves, on glyoxal formation the oxidative degradation three fatty acid ethyl esters was measured. Ethyl linoleate, linolenate and arachidonate were oxidized by Fenton's reagent. Glyoxal formed these analysed gas chromatography after it had been derivatized to quinoxaline with 1,2-phenylenediamine. comparative study performed using alpha-tocopherol. Generally, alpha-tocopherol exhibited a greater at lower levels, whereas 2"-O-GIV showed than higher levels. more effective towards high numbers double bonds. dose-response but did not. Maximum inhibition 82% obtained oxidation 8 mumol 2"-O-GIV, maximum 77% observed 0.25