作者: E.D. Acheson
DOI: 10.1016/0002-9343(59)90280-3
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摘要: Recent technical advances have added greatly to the ease with which virological methods may be applied study of poliomyelitis and allied infection central nervous system. These techniques already borne abundant fruit in development a vaccine against poliomyelitis. The accurate appraisal preventive value such will depend on our ability diagnose accurately. It had long been believed that clinical features acute paralytic were sufficiently characteristic for confident diagnosis made grounds alone. This confidence has recently shaken by finding virus louping-ill (Russian spring–summer encephalomyelitis) produce similar picture, even United Kingdom. There is also suggestive but incomplete evidence Coxsackie B, Echo other viruses occasionally cause flaccid paralysis. position “non-paralytic” less secure can no longer established purpose this article review number obscure outbreaks illness, majority at first confused later differentiated epidemiologic grounds. Although investigations restricted fact deaths occurred, most careful virologic studies failed incriminate polio virus, or groups organisms, any known neurotrophic agent. compared, basis view they constitute entity discussed. Such information as available about etiology, prognosis treatment reviewed.