Infectious Disease Immunohistochemistry in Placentas from HIV-Positive and HIV-Negative Patients:

摘要: ABSTRACT Studies comparing placental pathology between human immunodeficiency virus (HIV)–positive and HIV-negative patients have shown conflicting results. In addition, few studies evaluated the infectious etiology of inflammation in HIV-positive patients. We examined a cohort placentas from 73 41 to gain better understanding spectrum inflammatory lesions. Bacterial viral immunohistochemistry (IHC) was run on subset (12 7 HIV-negative) with greatest amount inflammation. Although histologic differences were seen groups, chorioamnionitis higher stage placentas. An agent found by IHC 3 (2 Neisseria spp. 1 group B Streptococcus). One placenta showed gram-positive cocci fetal membranes; organisms not detected IHC. 2 patients, etiologic a...