Cell invasion through basement membranes: an anchor of understanding
DOI: 10.1016/J.TCB.2006.03.004
关键词:
摘要: To metastasize, cancer cells must acquire the ability to breach several basement membrane barriers. Cell invasions through membranes also occur during normal development and immune system function, enabling organ formation cell dispersal. The mechanisms that use cross in vivo remain elusive. In development, these complex inaccessible environments, which are difficult study vivo. Anchor-cell invasion Caenorhabditis elegans is a simple, visually experimentally accessible model of beginning reveal network cellular molecular control regulate fundamental process membranes.
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