Carcinosarcoma and sarcomatoid carcinoma of the stomach: Two case reports.

摘要: Rationale Carcinosarcoma and sarcomatoid carcinoma of the stomach are rare, malignant, biphasic tumors with high mortality. The differential diagnosis these 2 diseases remains challenging. In present study, we cases carcinosarcoma stomach. Patient concerns A 54-year-old woman was admitted complaints epigastric pain for 4 months, but she became serious 10 days accompanied by melena. 75-year-old man 1 month. Diagnosis female had a Borrmann type III irregular ulcerative lesion (5.0 × 4.0 1.0 cm) originating from gastric antrum. male I tumor polypoid exophytic 2.0 in fundus near cardia. Both were identified as malignant neoplasms endoscopic biopsy further confirmed performing laparoscopic proximal gastrectomy, esophagogastrostomy, palliative distal subtotal gastrectomy. postoperative histopathological morphology immunohistochemistry studies revealed respectively. Interventions patient subsequently underwent laparoscopy-assisted radical gastrectomy cancer followed systemic chemotherapy oxaliplatin plus tegafur. esophagogastrostomy performed. Outcomes mixture little poorly-differentiated adenocarcinoma abundant spindle cell elements, is still alive healthy up to date half years after surgery phone follow-up. both fibrosarcoma single tumor, died month operation. Lessons study provides insight into clinical findings, diagnosis, prognosis carcinosarcomas carcinomas More needed future.