Remodeling the estrogen receptor model
作者： Jack Gorski , Wade Welshons , Dennis Sakai
DOI: 10.1016/0303-7207(84)90079-0
关键词:
摘要: The estrogen receptor model has revised to make it compatible with new data on subcellular localization of the and physical characteristics solubilized versus immobilized receptors. Our current suggests that receptors, or without bound estrogen, are present in nuclear fraction. Furthermore, behaves as if were some constituent at all times. Thus, association estrogen-free (unbound receptor) a target site nucleus is considered be critical event defining nature response estrogenic hormones.
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