Amino-Terminal Pro–B-Type Natriuretic Peptides and Prognosis in Chronic Heart Failure

摘要: In patients with chronic heart failure (HF), amino-terminal pro–B-type natriuretic peptide (NT-proBNP) levels are among the strongest independent predictors of hazard, and their measurement is useful for prognostication across entire spectrum HF disease severity. HF, repeated determinations NT-proBNP appear to convey additional prognostic value relevant adverse outcomes, including death or hospitalization. Although “hard targets” values not entirely defined, morbidity mortality in increase markedly an concentration >1,000 ng/L. Confounding factors (such as renal function obesity) should be kept mind when prognostically evaluating using measurements; however, retained these patients. Thus, serial assessment valuable outpatients, and, such, a at each patient visit following changes clinical stability recommended.