Specific chromosome defect associated with human small-cell lung cancer; deletion 3p(14-23)
作者： J Whang-Peng , C. Kao-Shan , E. Lee , P. Bunn , D. Carney
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摘要: A specific, acquired chromosomal abnormality (deletion 3p) has been found in at least one chromosome 3 100 percent of the metaphases 12 cell lines cultured from human small-cell lung cancer tissue and 2-day tumor culture specimens three patients. Analysis shortest region overlap shows deletion to be 3p(14-23). This specific change was not seen five other than or two lymphoblastoid cells patients whose tumors had 3p deletion.
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John D. Minna, Adi F. Gazdar, Stephen B. Baylin, Edward K. Russell, Paul A. Bunn, Harvie L. Sims, Desmond N. Carney, John G. Guccion, Establishment of Continuous, Clonable Cultures of Small-Cell Carcinoma of the Lung Which Have Amine Precursor Uptake and Decarboxylation Cell Properties Cancer Research. ,vol. 40, pp. 3502- 3507 ,(1980)
P.S. Moorhead, P.C. Nowell, W.J. Mellman, D.M. Battips, D.A. Hungerford, Chromosome preparations of leukocytes cultured from human peripheral blood Experimental Cell Research. ,vol. 20, pp. 613- 616 ,(1960) , 10.1016/0014-4827(60)90138-5
F.J. Tapia, A.J.A. Barbosa, P.J. Marangos, J.M. Polak, S.R. Bloom, C. Dermody, A.G.E. Pearse, NEURON-SPECIFIC ENOLASE IS PRODUCED BY NEUROENDOCRINE TUMOURS The Lancet. ,vol. 317, pp. 808- 811 ,(1981) , 10.1016/S0140-6736(81)92682-9
Frances E. Arrighi, T.C. Hsu, Localization of heterochromatin in human chromosomes Cytogenetic and Genome Research. ,vol. 10, pp. 81- 86 ,(1971) , 10.1159/000130130
John D. Minna, Adi F. Gazdar, Elisabeth Simms, Paul G. Abrams, Growth of Human Small Cell (Oat Cell) Carcinoma of the Lung in Serum-free Growth Factor-Supplemented Medium Cancer Research. ,vol. 40, pp. 4356- 4363 ,(1980)
Marina Seabright, A RAPID BANDING TECHNIQUE FOR HUMAN CHROMOSOMES The Lancet. ,vol. 298, pp. 971- 972 ,(1971) , 10.1016/S0140-6736(71)90287-X
A F Gazdar, S B Baylin, M H Zweig, D N Carney, A C Van Steirteghen, J D Minna, Levels of Creatine Kinase and Its BB Isoenzyme in Lung Cancer Specimens and Cultures Cancer Research. ,vol. 41, pp. 2773- 2777 ,(1981)
Cytogenetic Diagnosis of Cancer: Abnormalities of Chromosomes and Polyploid Levels in the Bone Marrow of Patients With Small Cell Anaplastic Carcinoma of the Lung Journal of the National Cancer Institute. ,vol. 61, pp. 1065- 1075 ,(1978) , 10.1093/JNCI/61.4.1065