Immunological activity of chitin and its derivatives.

摘要: The effect of chitin and its derivatives on the activation peritoneal macrophages in vivo, suppression tumour growth syngeneic mice protection host against bacterial infection was examined. Thirty percent deacetylated (30% DA-chitin), 70% DA-chitin carboxymethyl-chitin (CM-chitin) induced cytotoxic most effectively. Chitosan, hydroxyethyl-chitin, dihydroxypropyl-chitin (DHP-chitin) DHP-chitosan had moderate activities. Phosphorylated-, sulphonated- or acetyl-chitin, however, were less effective. Both active Meth-A BALB/c mice, 30% a effect. For stimulation non-specific resistance Escherichia coli infection,