Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
作者： Niels de Wind , Marleen Dekker , Anton Berns , Miroslav Radman , Hein te Riele
DOI: 10.1016/0092-8674(95)90319-4
关键词:
摘要: To investigate the role of the presumed DNA mismatch repair (MMR) gene Msh2 in genome stability and tumorigenesis, we have generated cells and mice that are deficient for the gene…
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