Hepatitis E virus (HEV)—The Future

作者: Joachim Denner

DOI: 10.3390/V11030251

关键词:

摘要: Hepatitis (HEV) is widely distributed in pigs and transmitted with increasing numbers to humans by contact pigs, contaminated food blood transfusion. The virus mostly apathogenic but may enhance the pathogenicity of other pig viruses. In humans, infection can lead acute chronic hepatitis extrahepatic manifestations. order stop emerging infection, effective counter-measures are required. First all, transmission products be prevented screening all donations. Meat sausages should appropriately cooked. Elimination from entire pork production achieved sensitive testing elimination programs including early weaning, colostrum deprivation, Caesarean delivery, embryo transfer, treatment antivirals, protection de novo possibly vaccination. addition, water, shellfish, vegetables, fruits HEV-contaminated manure avoided. A special situation given xenotransplantation using cells, tissues or organs alleviate lack human transplants. HEV animals consistent One Health concept, preventing subclinical infections as well disease.

参考文章(89)
Morgane Salines, Elodie Barnaud, Mathieu Andraud, Florent Eono, Patricia Renson, Olivier Bourry, Nicole Pavio, Nicolas Rose, Hepatitis E virus chronic infection of swine co-infected with Porcine Reproductive and Respiratory Syndrome Virus Veterinary Research. ,vol. 46, pp. 55- 55 ,(2015) , 10.1186/S13567-015-0207-Y
M. A. Beale, K. Tettmar, R. Szypulska, R. S. Tedder, S. Ijaz, Is there evidence of recent hepatitis E virus infection in English and North Welsh blood donors Vox Sanguinis. ,vol. 100, pp. 340- 342 ,(2011) , 10.1111/J.1423-0410.2010.01412.X
J. S. Shin, J. M. Kim, J. S. Kim, B. H. Min, Y. H. Kim, H. J. Kim, J. Y. Jang, I. H. Yoon, H. J. Kang, J. Kim, E. S. Hwang, D. G. Lim, W. W. Lee, J. Ha, K. C. Jung, S. H. Park, S. J. Kim, C. G. Park, Long-term control of diabetes in immunosuppressed nonhuman primates (NHP) by the transplantation of adult porcine islets. American Journal of Transplantation. ,vol. 15, pp. 2837- 2850 ,(2015) , 10.1111/AJT.13345
Andre Lindquist, Anh Hoang, Lee Vang, Maria Piron, Natàlia Casamitjana, Marco Koppelman, Lisa Danzig, Jeffrey M. Linnen, Sílvia Sauleda, Edgar Ong, Marta Bes, Alanna Janssen, Robin Cory, Maria Babizki, Tim Shin, Seroprevalence of hepatitis E virus (HEV) and detection of HEV RNA with a transcription-mediated amplification assay in blood donors from Catalonia (Spain). Transfusion. ,vol. 55, pp. 972- 979 ,(2015) , 10.1111/TRF.12929
Shao-Wei Li, Qinjian Zhao, Ting Wu, Shu Chen, Jun Zhang, Ning-Shao Xia, The development of a recombinant hepatitis E vaccine HEV 239. Human Vaccines & Immunotherapeutics. ,vol. 11, pp. 908- 914 ,(2015) , 10.1080/21645515.2015.1008870
David Juhl, Sally A. Baylis, Johannes Blümel, Siegfried Görg, Holger Hennig, Seroprevalence and incidence of hepatitis E virus infection in German blood donors. Transfusion. ,vol. 54, pp. 49- 56 ,(2014) , 10.1111/TRF.12121
Hélène Chaussade, Emma Rigaud, Aurore Allix, Audrey Carpentier, Antoine Touzé, Didier Delzescaux, Patrick Choutet, Nathalie Garcia-Bonnet, Pierre Coursaget, Hepatitis E virus seroprevalence and risk factors for individuals in working contact with animals. Journal of Clinical Virology. ,vol. 58, pp. 504- 508 ,(2013) , 10.1016/J.JCV.2013.08.030
Sven Pischke, Pothakamuri V. Suneetha, Christine Baechlein, Hannelore Barg-Hock, Albert Heim, Nassim Kamar, Jerome Schlue, Christian P. Strassburg, Frank Lehner, Regina Raupach, Birgit Bremer, Peter Magerstedt, Markus Cornberg, Frauke Seehusen, Wolfgang Baumgaertner, Juergen Klempnauer, Jacques Izopet, Michael P. Manns, B. Grummer, Heiner Wedemeyer, Hepatitis E virus infection as a cause of graft hepatitis in liver transplant recipients Liver Transplantation. ,vol. 16, pp. 74- 82 ,(2010) , 10.1002/LT.21958
Yanis Bouamra, René Gérolami, Jean-Pierre Arzouni, Jean-Charles Grimaud, Pierre Lafforgue, Marjorie Nelli, Natacha Tivoli, Audrey Ferretti, Anne Motte, Philippe Colson, Emergence of autochthonous infections with hepatitis E virus of genotype 4 in Europe. Intervirology. ,vol. 57, pp. 43- 48 ,(2014) , 10.1159/000354801
Shuchin Tei, Naoto Kitajima, Kazuaki Takahashi, Shunji Mishiro, Zoonotic transmission of hepatitis E virus from deer to human beings The Lancet. ,vol. 362, pp. 371- 373 ,(2003) , 10.1016/S0140-6736(03)14025-1