作者: F. Vacca , C. Scott , J. Gruenberg
DOI: 10.1016/B978-0-12-394447-4.20017-5
关键词:
摘要: Late endosome and lysosomes form the second major membrane network along endocytic pathway, after early/recycling endosomes, as such, late endosomes function last portal before lysosomes. In mammalian cells, they also link endosomal system to other cellular destinations, including trans-Golgi complex plasma membrane. Finally it has become clear in recent years that operate a sensing signaling organelle informs cell about its nutrient supply situation.