Oncogenic conversion by regulatory changes in transcription factors

作者: Benjamin Lewin

DOI: 10.1016/0092-8674(91)90640-K

关键词:

摘要: In this review ,I shall adress the relationship between retroviral-transforming v-onc genes and c-onc coding for transcription factors to ask whether changes in control of may account generation oncogenic phenotype .As with other classes oncogenes,we enquire expression patterns cellular proto-oncogenes offer any insights into specifity their derivatives.

参考文章(54)
M. Zerial, L. Toschi, R. P. Ryseck, M. Schuermann, R. Müller, R. Bravo, The product of a novel growth factor activated gene, fos B, interacts with JUN proteins enhancing their DNA binding activity. The EMBO Journal. ,vol. 8, pp. 805- 813 ,(1989) , 10.1002/J.1460-2075.1989.TB03441.X
A. Muñoz, M. Zenke, U. Gehring, J. Sap, H. Beug, B. Vennström, Characterization of the hormone-binding domain of the chicken c-erbA/thyroid hormone receptor protein. The EMBO Journal. ,vol. 7, pp. 155- 159 ,(1988) , 10.1002/J.1460-2075.1988.TB02795.X
T D Gilmore, H M Temin, v-rel oncoproteins in the nucleus and in the cytoplasm transform chicken spleen cells. Journal of Virology. ,vol. 62, pp. 703- 714 ,(1988) , 10.1128/JVI.62.3.703-714.1988
M Hannink, H M Temin, Transactivation of gene expression by nuclear and cytoplasmic rel proteins. Molecular and Cellular Biology. ,vol. 9, pp. 4323- 4336 ,(1989) , 10.1128/MCB.9.10.4323
Peter Angel, Masayoshi Imagawa, Robert Chiu, Bernd Stein, Richard J. Imbra, Hans J. Rahmsdorf, Carsten Jonat, Peter Herrlich, Michael Karin, Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor Cell. ,vol. 49, pp. 729- 739 ,(1987) , 10.1016/0092-8674(87)90611-8
B. Franza, F. Rauscher, S. Josephs, T Curran, The Fos complex and Fos-related antigens recognize sequence elements that contain AP-1 binding sites Science. ,vol. 239, pp. 1150- 1153 ,(1988) , 10.1126/SCIENCE.2964084
Roland Schüle, Pundl Rangarajan, Steven Kliewer, Lynn J. Ransone, Jack Bolado, Na Yang, Inder M. Verma, Ronald M. Evans, Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor Cell. ,vol. 62, pp. 1217- 1226 ,(1990) , 10.1016/0092-8674(90)90397-W
Jochen Schütte, Jean Viallet, Marion Nau, Shoshana Segal, Joseph Fedorko, John Minna, jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun Cell. ,vol. 59, pp. 987- 997 ,(1989) , 10.1016/0092-8674(89)90755-1