CANCER: Enhanced: Addiction to Oncogenes--the Achilles Heal of Cancer

作者: I. B. Weinstein

DOI: 10.1126/SCIENCE.1073096

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摘要: A series of recent studies are providing tantalizing hints new therapeutic approaches for combating cancer. In his Perspective, Weinstein discusses work ( Jain et al.) demonstrating that even brief inactivation an oncogene can permanently reverse the malignant phenotype some types tumor.

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