Reversibility of acute B-cell leukaemia induced by BCR-ABL1.

作者: Claudia S. Huettner , Pu Zhang , Richard A. Van Etten , Daniel G. Tenen

DOI: 10.1038/71691

关键词: MyelogenousOncogeneImmunologyBiologyTransgenic ModelLeukemiaPenetranceCancerReversionChromosomal translocation

摘要: … associated with different forms of leukaemia 2 . The most common form, p210 BCR–ABL1, is … the fusion protein is required for maintenance of leukaemia. We tested whether abolition of …

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