Molecular analysis of PIK3CA, BRAF, and RAS oncogenes in periampullary and ampullary adenomas and carcinomas.
作者： Frank Schönleben , Wanglong Qiu , John D. Allendorf , John A. Chabot , Helen E. Remotti
DOI: 10.1007/S11605-009-0917-4
关键词:
摘要: Background Mutations of KRAS are known to occur in periampullary and ampullary adenomas carcinomas. However, nothing is about NRAS, HRAS, BRAF, PIK3CA mutations these tumors. While oncogenic BRAF contributes the tumorigenesis both pancreatic ductal adenocarcinoma intraductal papillary mucinous neoplasms/carcinomas (IPMN/IPMC), were only detected IPMN/IPMC. This study aimed elucidate possible roles development
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Juan M. Sarmiento, David M. Nagorney, Michael G. Sarr, Michael B. Farnell, Periampullary cancers: are there differences? Surgical Clinics of North America. ,vol. 81, pp. 543- 555 ,(2001) , 10.1016/S0039-6109(05)70142-0
R D Odze, B V Bapat, A Mitri, S Gallinger, A A Vivona, T C Berk, C P O'Beirne, SOMATIC APC AND K-RAS CODON 12 MUTATIONS IN PERIAMPULLARY ADENOMAS AND CARCINOMAS FROM FAMILIAL ADENOMATOUS POLYPOSIS PATIENTS Oncogene. ,vol. 10, pp. 1875- 1878 ,(1995)
Julio A. Aguirre-Ghiso, Liliana Ossowski, Yeriel Estrada, David Liu, ERKMAPK Activity as a Determinant of Tumor Growth and Dormancy; Regulation by p38SAPK Cancer Research. ,vol. 63, pp. 1684- 1695 ,(2003)
Marcia S Brose, Patricia Volpe, Michael Feldman, Madhu Kumar, Irum Rishi, Renee Gerrero, Eugene Einhorn, Meenhard Herlyn, John Minna, Andrew Nicholson, Jack A Roth, Steven M Albelda, Helen Davies, Charles Cox, Graham Brignell, Philip Stephens, P Andrew Futreal, Richard Wooster, Michael R Stratton, Barbara L Weber, None, BRAF and RAS mutations in human lung cancer and melanoma Cancer Research. ,vol. 62, pp. 6997- 7000 ,(2002)
Ralph H. Hruban, Taylor A. Sohn, Mieke Schutte, Charles J. Yeo, Stephan A. Hahn, Scott E. Kern, Steven N. Goodman, Marianna Zahurak, Ester Rozenblum, Michael Goggins, Shawn Panzer, Tumor-suppressive Pathways in Pancreatic Carcinoma Cancer Research. ,vol. 57, pp. 1731- 1734 ,(1997)
Eric S. Calhoun, Jessa B. Jones, Raheela Ashfaq, Volkan Adsay, Suzanne J. Baker, Virginia Valentine, Paula M. Hempen, Werner Hilgers, Charles J. Yeo, Ralph H. Hruban, Scott E. Kern, BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) Mutations in Distinct Subsets of Pancreatic Cancer: Potential Therapeutic Targets American Journal of Pathology. ,vol. 163, pp. 1255- 1260 ,(2003) , 10.1016/S0002-9440(10)63485-2
T SOHN, C YEO, J CAMERON, L KONIARIS, S KAUSHAL, R ABRAMS, P SAUTER, J COLEMAN, R HRUBAN, K LILLEMOE, Resected adenocarcinoma of the pancreas-616 patients: results, outcomes, and prognostic indicators. Journal of Gastrointestinal Surgery. ,vol. 4, pp. 567- 579 ,(2000) , 10.1016/S1091-255X(00)80105-5
Charles J. Yeo, John L. Cameron, Taylor A. Sohn, Keith D. Lillemoe, Henry A. Pitt, Mark A. Talamini, Ralph H. Hruban, Sarah E. Ord, Patricia K. Sauter, JoAnn Coleman, Marianna L. Zahurak, Louise B. Grochow, Ross A. Abrams, Six hundred fifty consecutive pancreaticoduodenectomies in the 1990s: pathology, complications, and outcomes. Annals of Surgery. ,vol. 226, pp. 248- 260 ,(1997) , 10.1097/00000658-199709000-00004
Carole Peyssonnaux, Alain Eychène, The Raf/MEK/ERK pathway: new concepts of activation Biology of the Cell. ,vol. 93, pp. 53- 62 ,(2001) , 10.1016/S0248-4900(01)01125-X
Ralph H. Hruban, Robb E. Wilentz, Scott E. Kern, Genetic progression in the pancreatic ducts. American Journal of Pathology. ,vol. 156, pp. 1821- 1825 ,(2000) , 10.1016/S0002-9440(10)65054-7