作者: Rasnik K. Singh , Kristina M. Lee , Ivan Vujkovic-Cvijin , Derya Ucmak , Benjamin Farahnik
DOI: 10.1016/J.AUTREV.2016.01.004
关键词:
摘要: IL-17 is involved in the pathogenesis of several autoimmune diseases; however its role vitiligo has not been well defined. Emerging human and mouse studies have demonstrated that systemic, tissue, cellular levels are elevated vitiligo. Many also shown significant positive correlations between these disease activity, extent, severity. Treatments improve vitiligo, such as ultraviolet B phototherapy, modulate levels. This review synthesizes our current understanding how may influence at molecular level. implications for defining new biomarkers treatments.