Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function
作者： Takuro Wada , Xiaolan Qian , Mark I. Greene
DOI: 10.1016/0092-8674(90)90697-D
关键词:
摘要: We have used cross-linking reagents on cell lines expressing both p185 neu and EGFR. The lysates of the cells were precipitated with anti-p185 neu or anti-EGFR antibodies. These …
elsevier.com
sci-hub.se 参考文章(44)
Drebin Ja, Link Vc, Greene Mi, Monoclonal antibodies reactive with distinct domains of the neu oncogene-encoded p185 molecule exert synergistic anti-tumor effects in vivo. Oncogene. ,vol. 2, pp. 273- ,(1988)
D. F. Stern, M. P. Kamps, EGF-stimulated tyrosine phosphorylation of p185neu: a potential model for receptor interactions. The EMBO Journal. ,vol. 7, pp. 995- 1001 ,(1988) , 10.1002/J.1460-2075.1988.TB02906.X
C. R. King, I. Borrello, F. Bellot, P. Comoglio, J. Schlessinger, Egf binding to its receptor triggers a rapid tyrosine phosphorylation of the erbB-2 protein in the mammary tumor cell line SK-BR-3. The EMBO Journal. ,vol. 7, pp. 1647- 1651 ,(1988) , 10.1002/J.1460-2075.1988.TB02991.X
C Cochet, O Kashles, E M Chambaz, I Borrello, C R King, J Schlessinger, Demonstration of epidermal growth factor-induced receptor dimerization in living cells using a chemical covalent cross-linking agent. Journal of Biological Chemistry. ,vol. 263, pp. 3290- 3295 ,(1988) , 10.1016/S0021-9258(18)69070-2
R J Davis, Independent mechanisms account for the regulation by protein kinase C of the epidermal growth factor receptor affinity and tyrosine-protein kinase activity. Journal of Biological Chemistry. ,vol. 263, pp. 9462- 9469 ,(1988) , 10.1016/S0021-9258(19)76563-6
H.T. Haigler, F.R. Maxfield, M.C. Willingham, I. Pastan, Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells. Journal of Biological Chemistry. ,vol. 255, pp. 1239- 1241 ,(1980) , 10.1016/S0021-9258(19)86019-2
A C King, P Cuatrecasas, Resolution of high and low affinity epidermal growth factor receptors. Inhibition of high affinity component by low temperature, cycloheximide, and phorbol esters. Journal of Biological Chemistry. ,vol. 257, pp. 3053- 3060 ,(1982) , 10.1016/S0021-9258(19)81072-4
Alan L. Schechter, David F. Stern, Lalitha Vaidyanathan, Stuart J. Decker, Jeffrey A. Drebin, Mark I. Greene, Robert A. Weinberg, The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen. Nature. ,vol. 312, pp. 513- 516 ,(1984) , 10.1038/312513A0
M. Boni-Schnetzler, P. F. Pilch, Mechanism of epidermal growth factor receptor autophosphorylation and high-affinity binding. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 84, pp. 7832- 7836 ,(1987) , 10.1073/PNAS.84.22.7832
Jeffrey A. Drebin, Victoria C. Link, David F. Stern, Robert A. Weinberg, Mark I. Greene, Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies. Cell. ,vol. 41, pp. 695- 706 ,(1985) , 10.1016/S0092-8674(85)80050-7