Synthesis, characterization, crystal structure and antitumor activity of organotin(IV) compounds bearing ferrocenecarboxylic acid

摘要: Four new organotin(IV) complexes [(Bu 3 Sn)(FcCOO)] n ( 1 ), [(μ-Bu 2 Sn) (μ-Bu SnFcCOO) (μ -O) (μ-OCH ) ] [Ph Sn(FcCOO)(H O)](phen) and [{Ph Sn(FcCOO)} (4,4′-bipy)] 4 [Fc = (η 5 -C H )Fe(η )] have been synthesized characterized by elemental analyses, IR, 13 C) NMR spectra X-ray single-crystal diffraction analyses. The structure analyses show that all tin atoms in – are five-coordinated with trigonal bipyramid geometry. Complexes FcCOOH undergo reversible one-electron oxidations methanol solution. antitumor activities of also tested. exhibit medium activity towards P388 cell lines Hela lines. but strong This may result from including the neutral molecules 1,10-phenanthroline 4,4′-bipy.