Miniaturized molecularly imprinted polymer extraction method for the gas chromatographic analysis of flavonoids.
作者： Yada Nolvachai , Chadin Kulsing , Reinhard I. Boysen , Milton T.W. Hearn , Philip J. Marriott
关键词:
摘要: In this study, the use of monolithic molecularly imprinted polymers in a micropipette tip format allowing simple and fast extraction flavonoids from standard solutions black tea sample is demonstrated. The polymer employed quercetin, methacrylic acid or 4-vinylpyridine, ethylene glycol dimethacrylate as template, functional monomer, cross-linker, respectively. Surface morphologies quercetin-imprinted corresponding nonimprinted were characterized by SEM. Extraction flavonoid standards was performed to evaluate selectivity recovery with these polymers. Flavonoid compositions aliquots eluted tips identified using GC flame ionization detection. Maximum specific capacities 0.2, 5.7, 16.0 mg/g for catechin, morin, respectively, obtained prepared acid, recoveries 99.8, 98.8, 95.4%, Efficient epicatechin, quercetin an apple-flavored achieved, GC-MS compound identification both extracted samples.
sci-hub.se 参考文章(34)
Chanbasha Basheer, Anbanandam Parthiban, Akhila Jayaraman, Hian Kee Lee, Suresh Valiyaveettil, None, Determination of alkylphenols and bisphenol-A. A comparative investigation of functional polymer-coated membrane microextraction and solid-phase microextraction techniques. Journal of Chromatography A. ,vol. 1087, pp. 274- 282 ,(2005) , 10.1016/J.CHROMA.2005.03.014
Reinhard I. Boysen, Milton T.W. Hearn, High Performance Liquid Chromatographic Separation Methods Comprehensive Natural Products II. ,vol. 9, pp. 5- 49 ,(2010) , 10.1016/B978-008045382-8.00183-0
Robert Weiss, Alexandra Molinelli, Michael Jakusch, Boris Mizaikoff, Molecular imprinting and solid phase extraction of flavonoid compounds. Bioseparation. ,vol. 10, pp. 379- 387 ,(2001) , 10.1023/A:1021554106297
Vusumzi Pakade, Ewa Cukrowska, Sofia Lindahl, Charlotta Turner, Luke Chimuka, Molecular imprinted polymer for solid‐phase extraction of flavonol aglycones from Moringa oleifera extracts Journal of Separation Science. ,vol. 36, pp. 548- 555 ,(2013) , 10.1002/JSSC.201200576
Yada Nolvachai, Philip J. Marriott, GC for flavonoids analysis: Past, current, and prospective trends Journal of Separation Science. ,vol. 36, pp. 20- 36 ,(2013) , 10.1002/JSSC.201200846
Mostafa Khajeh, Mousa Bohlooli, Hossein Hashemi, Imprinted Polymer Particles for Aluminum Uptake: Synthesis and Analytical Applications Journal of Macromolecular Science, Part A. ,vol. 46, pp. 526- 532 ,(2009) , 10.1080/10601320902797806
Wenpeng Zhang, Zilin Chen, Preparation of micropipette tip-based molecularly imprinted monolith for selective micro-solid phase extraction of berberine in plasma and urine samples. Talanta. ,vol. 103, pp. 103- 109 ,(2013) , 10.1016/J.TALANTA.2012.10.014
Xin Gao, Spencer J. Williams, Owen L. Woodman, Philip J. Marriott, Comprehensive two-dimensional gas chromatography, retention indices and time-of-flight mass spectra of flavonoids and chalcones Journal of Chromatography A. ,vol. 1217, pp. 8317- 8326 ,(2010) , 10.1016/J.CHROMA.2010.10.093
Alexandra Molinelli, Robert Weiss, Boris Mizaikoff, Advanced solid phase extraction using molecularly imprinted polymers for the determination of quercetin in red wine. Journal of Agricultural and Food Chemistry. ,vol. 50, pp. 1804- 1808 ,(2002) , 10.1021/JF011213Q
Manuela Curcio, Giuseppe Cirillo, Ortensia Ilaria Parisi, Francesca Iemma, Nevio Picci, Francesco Puoci, Quercetin-imprinted nanospheres as novel drug delivery devices. Journal of Functional Biomaterials. ,vol. 3, pp. 269- 282 ,(2012) , 10.3390/JFB3020269