Acute and chronic effects of domperidone on gastric emptying in diabetic autonomic neuropathy.
作者： M. Horowitz , P. E. Harding , B. E. Chatterton , P. J. Collins , D. J. C. Shearman
DOI: 10.1007/BF01318363
关键词:
摘要: Gastric emptying was studied with a double radioisotopic method in 12 patients insulin-dependent diabetes mellitus complicated by autonomic neuropathy and 22 control subjects. In the diabetics, acute chronic effects of oral domperidone on gastric emptying, symptoms gastroparesis, glycemic were assessed. solid liquid slower diabetics than controls (P less 0.001). Acute administration increased rate both 0.005). Domperidone most effective those greatest delay emptying. After (35-51 days), had no significant effect greater 0.05), but still increasing 0.025). Symptoms gastroparesis after
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