Clinicopathologic features of hypertrophic cardiomyopathy managed by cardiac transplantation

摘要: Abstract Clinical records, electrocardiographic, echocardiographic, hemodynamic and radionuclide data, the operatively excised hearts were reviewed in 10 patients (aged 19 to 46 years, mean 35) who had cardiac transplantation for hypertrophic cardiomyopathy. Severe congestive heat failure unassociated with outflow obstruction was indication 9 patients. During a pretransplantation period ringing from 45 312 months (mean 137) these patients, pulmonary artery wedge pressure increased ± 27 7 mm Hg, left ventricular ejection fraction decreased 51 11% 41 1%, end-diastolic dimension 42 6 48 4 mm, total 12-lead QRS voltage 209 50 156 mm. In explanted dilated cavities, 8 scars without significant narrowing of epicardial coronary arteries. The tenth patient nondilated cavity because recurrent, refractory syncope. Of 3 died within first month, another after transplantation. remaining have survived 20 54 39) are functional class I or II.