Subacute, tetracycline-responsive, granulomatous osteomyelitis in an adult man, consistent with Q fever infection.
作者： Cornelia Bayard , Alexis Dumoulin , Kristian Ikenberg , Huldrych F Günthard
关键词:
摘要: Osteomyelitis due to Coxiella burnetii infection is a rare condition in adults. We report the case of healthy young man presenting with subacute osteomyelitis left cheek bone, evolving gradually after an episode acute febrile illness. Histological evaluation confirmed granulomatous inflammation. Despite antibody titres not reaching standard cut-off for chronic Q fever (phase I IgG 1/160, phase II 1/2560), was radiologically and histologically confirmed. A 6-month course doxycycline/hydroxychloroquine brought clinical radiological cure while various conventional antibiotic treatments had failed improve condition. Currently, at follow-up, no relapse has occurred have declined. shorter than that used may be sufficient treat some cases.
core.ac.uk
uzh.ch
sci-hub.st 参考文章(14)
Adilia Warris, Chantal P. Bleeker-Rovers, Corine E. Delsing, Q Fever: Still More Queries than Answers Advances in Experimental Medicine and Biology. ,vol. 719, pp. 133- 143 ,(2012) , 10.1007/978-1-4614-0204-6_12
C. Landais, F. Fenollar, A. Constantin, C. Cazorla, C. Guilyardi, H. Lepidi, A. Stein, J. M. Rolain, D. Raoult, Q fever osteoarticular infection: four new cases and a review of the literature. European Journal of Clinical Microbiology & Infectious Diseases. ,vol. 26, pp. 341- 347 ,(2007) , 10.1007/S10096-007-0285-5
Matthieu Million, Lucile Bellevegue, Anne-Sophie Labussiere, Michal Dekel, Tristan Ferry, Philippe Deroche, Cristina Socolovschi, Serge Cammilleri, Didier Raoult, Culture-negative Prosthetic Joint Arthritis Related to Coxiella burnetii The American Journal of Medicine. ,vol. 127, pp. 786- ,(2014) , 10.1016/J.AMJMED.2014.03.013
S. Edouard, M. Million, H. Lepidi, J.-M. Rolain, P.-E. Fournier, B. La Scola, D. Grisoli, D. Raoult, Persistence of DNA in a Cured Patient and Positive Culture in Cases with Low Antibody Levels Bring into Question Diagnosis of Q Fever Endocarditis Journal of Clinical Microbiology. ,vol. 51, pp. 3012- 3017 ,(2013) , 10.1128/JCM.00812-13
Vicky Merhej, Pierre Tattevin, Matthieu Revest, Bastien Le Touvet, Didier Raoult, Q fever osteomyelitis: a case report and literature review. Comparative Immunology Microbiology and Infectious Diseases. ,vol. 35, pp. 169- 172 ,(2012) , 10.1016/J.CIMID.2011.12.008
E. Acquacalda, H. Montaudie, C. Laffont, P.-E. Fournier, C. Pulcini, A case of multifocal chronic Q fever osteomyelitis. Infection. ,vol. 39, pp. 167- 169 ,(2011) , 10.1007/S15010-010-0076-2
Didier Raoult, Chronic Q fever: Expert opinion versus literature analysis and consensus Journal of Infection. ,vol. 65, pp. 102- 108 ,(2012) , 10.1016/J.JINF.2012.04.006
Pierre-Edouard Fournier, Thomas J. Marrie, Didier Raoult, Diagnosis of Q fever. Journal of Clinical Microbiology. ,vol. 36, pp. 1823- 1834 ,(1998) , 10.1128/JCM.36.7.1823-1834.1998
A. Lecaillet, M.-N. Mallet, D. Raoult, J.-M. Rolain, Therapeutic impact of the correlation of doxycycline serum concentrations and the decline of phase I antibodies in Q fever endocarditis Journal of Antimicrobial Chemotherapy. ,vol. 63, pp. 771- 774 ,(2009) , 10.1093/JAC/DKP013
Clare Nourse, Anthony Allworth, Andrew Jones, Robert Horvath, Joe McCormack, Jeremy Bartlett, David Hayes, Jennifer M. Robson, Three cases of Q fever osteomyelitis in children and a review of the literature. Clinical Infectious Diseases. ,vol. 39, ,(2004) , 10.1086/424014