Localization of T lymphocytes and macrophages in fibrous and complicated human atherosclerotic plaques
作者： G.K. Hansson , L. Jonasson , B. Lojsthed , S. Stemme , O. Kocher
DOI: 10.1016/0021-9150(88)90074-3
关键词:
摘要: The cellular composition of aortic atherosclerotic plaques was analyzed by immunocytochemistry using cell type-specific monoclonal antibodies. T lymphocytes and monocytes/macrophages were detected both in early, fibrous plaques, more advanced, complicated ones. Many smooth muscle cells these expressed the class II MHC antigen, HLA-DR. Since this antigen is inducible products, our findings suggest that cell-smooth interactions occur during atherogenesis.
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