Solid Lipid Nanoparticles to Improve Brain Drug Delivery

作者: Paolo Blasi , Aurélie Schoubben , Stefano Giovagnoli , Carlo Rossi , Maurizio Ricci

DOI: 10.1002/9783527610419.NTLS0257

关键词:

摘要: The sections in this article are Introduction The General Problem of Brain Drug Delivery Basic Physiology Brain Drug-Delivery Strategies Solid Lipid Nanoparticles for Delivery General Information Physico-Chemical Aspects Packing and SLN Structure Surfactants SLNs Targeting Evidence Accumulation SLN Potentiality Imaging Toxicity Issues Concluding Remarks Keywords: solid lipid nanoparticles; colloids; drug targeting; brain delivery; blood–brain barrier; neurovascular unit; polysorbate-coated nanoparticles

参考文章(155)
Dale E. Bredesen, Robert M. Levy, Central nervous system dysfunction in acquired immunodeficiency syndrome. Journal of Acquired Immune Deficiency Syndromes. ,vol. 1, pp. 41- 64 ,(1988)
Rainer H. Müller, Dörte Rühl, Stephan Runge, Kai Schulze‐Forster, Wolfgang Mehnert, Cytotoxicity of Solid Lipid Nanoparticles as a Function of the Lipid Matrix and the Surfactant Pharmaceutical Research. ,vol. 14, pp. 458- 462 ,(1997) , 10.1023/A:1012043315093
Andrea M. Brioschi, Sara Calderoni, Gian Paolo Zara, Lorenzo Priano, Maria Rosa Gasco, Alessandro Mauro, Solid lipid nanoparticles for brain tumors therapy: State of the art and novel challenges Progress in Brain Research. ,vol. 180, pp. 193- 223 ,(2009) , 10.1016/S0079-6123(08)80011-8
Pilar Calvo, Bruno Gouritin, Hélène Chacun, Didier Desmaële, Jean D'Angelo, Jean‐Pierre Noel, Dominique Georgin, Elias Fattal, Jean P. Andreux, Patrick Couvreur, Long-circulating PEGylated polycyanoacrylate nanoparticles as new drug carrier for brain delivery. Pharmaceutical Research. ,vol. 18, pp. 1157- 1166 ,(2001) , 10.1023/A:1010931127745
Carsten Olbrich, Oliver Kayser, Rainer Helmut Müller, Enzymatic Degradation of Dynasan 114 SLN – Effect of Surfactants and Particle Size Journal of Nanoparticle Research. ,vol. 4, pp. 121- 129 ,(2002) , 10.1023/A:1020159331420
Praveen Ballabh, Alex Braun, Maiken Nedergaard, The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiology of Disease. ,vol. 16, pp. 1- 13 ,(2004) , 10.1016/J.NBD.2003.12.016
Madjid Abes, Suresh S. Narine, Crystallization and phase behavior of fatty acid esters of 1,3-propanediol I: pure systems. Chemistry and Physics of Lipids. ,vol. 149, pp. 14- 27 ,(2007) , 10.1016/J.CHEMPHYSLIP.2007.05.001
Shicheng Yang, Jiabi Zhu, Yu Lu, Bingwen Liang, Changzheng Yang, Body Distribution of Camptothecin Solid Lipid Nanoparticles After Oral Administration Pharmaceutical Research. ,vol. 16, pp. 751- 757 ,(1999) , 10.1023/A:1018888927852
Renad N. Alyautdin, Valery E. Petrov, Klaus Langer, Achim Berthold, Dimitry A. Kharkevich, Jörg Kreuter, Delivery of loperamide across the blood-brain barrier with polysorbate 80-coated polybutylcyanoacrylate nanoparticles. Pharmaceutical Research. ,vol. 14, pp. 325- 328 ,(1997) , 10.1023/A:1012098005098