Solid lipid nanoparticles for brain tumors therapy: State of the art and novel challenges
作者： Andrea M. Brioschi , Sara Calderoni , Gian Paolo Zara , Lorenzo Priano , Maria Rosa Gasco
DOI: 10.1016/S0079-6123(08)80011-8
关键词: Cholesterylbutyrate 、 Cancer research 、 Brain tumor 、 Poor prognosis 、 Targeted drug delivery 、 Pathology 、 Angiogenesis 、 Solid lipid nanoparticle 、 Medicine
摘要: Malignant gliomas, despite aggressive multimodal therapies and adequate supportive care, still maintain poor prognosis. Solid lipid nanoparticles (SLN) are colloidal carriers that could be regarded as a highly flexible platform for brain tumor imaging therapeutical purposes. In this chapter we will first describe tumors characteristics conventional approaches. the subsequent sections, analyze SLN properties, effectiveness, future perspectives in both targeted treatment of malignant gliomas.
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