作者: Marina Korotkova , Lars Å. Hanson
DOI: 10.1016/S1084-2756(02)90124-7
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摘要: The immune system of the human newborn is very limited size. It expands rapidly, especially due to exposure gut microflora. Normally colonized with microbes from mother's intestinal flora at and after delivery. many defence factors milk include large amounts secretory IgA antibodies produced by lymphocytes which have migrated mammary glands. Therefore SIgA are mainly directed against previous recent Thus breastfeeding modulates early neonate's mucosa limits bacterial translocation through mucosa. This may be a major reason why protects efficiently neonatal septicaemia, as well several other infections. prevent infections already mucosal level. transplacentally obtained maternal IgG protect primarily in tissues do so cost cytokine-induced clinical symptoms, tissue engagement high energy consumption.