The Loss of Glutamate-GABA Harmony in Anxiety Disorders

摘要: The proper functioning of the central nervous system (CNS) depends on physiological homeostasis, which is itself maintained and regulated by two opposite forces acting independently to each other, flowing into a natural cycle always seeking balance. thing about main amino acid neurotransmitters, glutamate GABA, creating excitatory/inhibitory in brain. Together, these neurotransmitters constitute more than 90% all neurotransmission, leaving less 10% for others. Therefore, possibilities their mutual interaction determinates CNS. In Fig. 1, schematic balance presented, mirrors equilibrium between GABA (represented white dots) as black dots).