Exclusion of chromosomal mosaicism: tables of 90%, 95% and 99% confidence limits and comments on use

作者: E B Hook

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摘要: Tables specifically tailored to the exclusion of cytogenetic mosaicism at three confidence levels are presented. The consequences assumption independence in application binomial theorem this question discussed. tables most applicable number cells evaluated from cultures which all mitoses arrested first vitro division. For long-term conservatively separate colonies evaluated. If n have been phytohemagglutinin stimulated peripheral blood after 72 hr cultures, between n/2 and cells.

参考文章(3)
S. A. Midian, V. I. Alekhin, A. N. Chebotarev, N. P. Kuleshov, N. P. Bochkov, Population cytogenetic investigation of newborns in Moscow. Human Genetics. ,vol. 22, pp. 139- 152 ,(1974) , 10.1007/BF00278453
Ernest B. Hook, Norma H. Hatcher, Orysia J. Calka, Apparent "in situ" clone of cytogenetically marked ataxia-telangiectasia lymphocytes. Human Genetics. ,vol. 30, pp. 251- 257 ,(1975) , 10.1007/BF00279190
N H Hatcher, E B Hook, Early in vitro division of PHA stimulated cord blood lymphocytes: implications for study of chromosome breakage. American Journal of Human Genetics. ,vol. 28, pp. 290- 293 ,(1976)