Temporal monitoring of liver and kidney lesions in contaminated East Greenland polar bears (Ursus maritimus) during 1999-2010.

作者: Christian Sonne , Robert J. Letcher , Pall S. Leifsson , Frank F. Rigét , Thea Ø. Bechshøft

DOI: 10.1016/J.ENVINT.2012.07.002

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摘要: Abstract Organohalogen contaminants bioaccumulate to high concentrations in tissues of polar bears ( Ursus maritimus ). The exposure levels are the order be toxic inner organs like liver and kidney. We therefore investigated temporal development lesions (n = 115) kidney (n = 122) samples from East Greenland taken over 12 year period 1999 2010. Seven seven were observed which six age-related. Controlling for this, analyses showed that hepatic steatosis renal cell infiltrations, glomerular sclerosis tubular hyperplasia decreased time (all p  trans -nonachlor being positively associated with (p = 0.06) while dichlorodiphenyltrichloroethanes negatively (p = 0.02). These results suggest specific have or increased long-range transported organohalogen mercury may among co-factors responsible these observations. relationships important take into account when biomonitoring health pollution wildlife species such as bears.

参考文章(56)
R. Dietz, M.-P. Heide-Jørgensen, T. Härkönen, J. Teilmann, N. Valentin, Age determination of european harbour seal, Phoca Vitulina L. Sarsia. ,vol. 76, pp. 17- 21 ,(1991) , 10.1080/00364827.1991.10413461
John D. Bancroft, Marilyn Gamble, Theory and Practice of Histological Techniques ,(1990)
Peter C. Kennedy, K. V. F. Jubb, Pathology of Domestic Animals ,(2013)
Jacob Churg, Richard J. Glassock, Jay Bernstein, Renal Disease: Classification and Atlas of Glomerular Diseases ,(1982)
Robert J. Letcher, Wouter A. Gebbink, Christian Sonne, Erik W. Born, Melissa A. McKinney, Rune Dietz, Bioaccumulation and biotransformation of brominated and chlorinated contaminants and their metabolites in ringed seals (Pusa hispida) and polar bears (Ursus maritimus) from East Greenland. Environment International. ,vol. 35, pp. 1118- 1124 ,(2009) , 10.1016/J.ENVINT.2009.07.006
G ASMUND, K VORKAMP, S BACKUS, M COMBA, An update on analytical methods, quality assurance and quality control used in the Greenland AMAP programme: 1999-2002. Science of The Total Environment. ,vol. 331, pp. 233- 245 ,(2004) , 10.1016/J.SCITOTENV.2004.03.031
Thea Ø. Bechshøft, Christian Sonne, Frank F. Rigét, Robert J. Letcher, Melinda A. Novak, Elizabeth Henchey, Jerrold S. Meyer, Igor Eulaers, Veerle L. B. Jaspers, Adrian Covaci, Rune Dietz, Polar bear stress hormone cortisol fluctuates with the North Atlantic Oscillation climate index Polar Biology. ,vol. 36, pp. 1525- 1529 ,(2013) , 10.1007/S00300-013-1364-Y
A.J. Rawson, G.W. Patton, S. Hofmann, G.G. Pietra, L. Johns, Liver Abnormalities Associated with Chronic Mercury Accumulation in Stranded Atlantic Bottlenosed Dolphins Ecotoxicology and Environmental Safety. ,vol. 25, pp. 41- 47 ,(1993) , 10.1006/EESA.1993.1005