Improved tretinoin photostability in a topical nanomedicine replacing original liquid suspension with spray-dried powder with no loss of effectiveness.

作者: M. C. L. Marchiori , R. H. Rascovetzki , A. F. Ourique , L. A. Rigo , C. B. Silva

DOI: 10.3109/03639045.2012.691510

关键词:

摘要: … in the photostability of tretinoin in dermatological … higher tretinoin photostability. To the best of our knowledge these approaches to obtaining hydrogels with better tretinoin photostability …

参考文章(36)
Richard Berger, Ronald Rizer, Alicia Barba, David Wilson, Daniel Stewart, Rachel Grossman, Marge Nighland, Jonathan Weiss, Tretinoin gel microspheres 0.04% versus 0.1% in adolescents and adults with mild to moderate acne vulgaris: A 12-week, multicenter, randomized, double-blind, parallel-group, phase IV trial Clinical Therapeutics. ,vol. 29, pp. 1086- 1097 ,(2007) , 10.1016/J.CLINTHERA.2007.06.021
Milão D, Richter W, Knorst Mt, Guterres Ss, Hydrophilic gel containing nanocapsules of diclofenac: development, stability study and physico-chemical characterization. Die Pharmazie. ,vol. 58, pp. 325- 329 ,(2003)
M. C. L. Marchiori, A. F. Ourique, C. de B. da Silva, R. P. Raffin, A. R. Pohlmann, S. S. Guterres, R. C. R. Beck, Spray-dried powders containing tretinoin-loaded engineered lipid-core nanocapsules: development and photostability study. Journal of Nanoscience and Nanotechnology. ,vol. 12, pp. 2059- 2067 ,(2012) , 10.1166/JNN.2012.5192
Karina Paese, Alessandro Jäger, Fernanda S. Poletto, Eduardo Fonseca Pinto, Bartira Rossi-Bergmann, Adriana R. Pohlmann, Sílvia S. Guterres, Semisolid formulation containing a nanoencapsulated sunscreen: effectiveness, in vitro photostability and immune response. Journal of Biomedical Nanotechnology. ,vol. 5, pp. 240- 246 ,(2009) , 10.1166/JBN.2009.1028
Anil K. Singla, Deepika Aggarwal, Sanjay Garg, Spreading of Semisolid Formulations ,(2002)
Anil K Singla, Deepika Aggarwal, Alka Garg, Sanjay Garg, Spreading of semisolid formulations: An update Pharmaceutical technology. ,vol. 26, pp. 84- 105 ,(2002)
Juliana M. Fachinetto, Solange B. Tedesco, Aline F. Ourique, Ruy Carlos Ruver Beck, Antônio C.F. Silva, Tretinoin-loaded polymeric nanocapsules: evaluation of the potential toimprove the antiproliferative activities on Allium cepa root-tip compared to the free drug Latin American Journal of Pharmacy. ,(2008)
Adriana R. Pohlmann, Sílvia S. Guterres, Marta P. Alves, Polymeric nanoparticles, nanospheres and nanocapsules, for cutaneous applications. Drug Target Insights. ,vol. 2, pp. 147- 157 ,(2007) , 10.4137/DTI.S0
Maria Manconi, Chiara Sinico, Donatella Valenti, Francesco Lai, Anna M. Fadda, Niosomes as carriers for tretinoin: III. A study into the in vitro cutaneous delivery of vesicle-incorporated tretinoin International Journal of Pharmaceutics. ,vol. 311, pp. 11- 19 ,(2006) , 10.1016/J.IJPHARM.2005.11.045