A prospective evaluation of the role of transient elastography for the detection of hepatic fibrosis in type 2 diabetes without overt liver disease.
作者： Stephen P. Casey , William W. Kemp , Catriona A. McLean , Duncan J. Topliss , Leon A. Adams
DOI: 10.3109/00365521.2012.677955
关键词:
摘要: Abstract Background. Type 2 diabetes mellitus (T2DM) is a major risk factor for the development of non-alcoholic fatty liver disease (NAFLD) and subsequently hepatic fibrosis. Transient elastography (TE) rapid, reproducible non-invasive test that may be appropriate as screening tool presence AIM: Assess utility TE fibrosis in T2DM population with no known disease. Methods. patients without were included. Patients assessed addition to biochemical parameters. Results. A successful evaluation could obtained 74 81 (91%) included subjects. Of these, 26 (35%) had stiffness measurement (LSM) ≥7.65 kPa. Sixteen these subjects confirmatory biopsies significant (≥F2 fibrosis) present 12 (75%) cirrhosis diagnosed 15/16 (94%) histological steatohepatitis. Compared those lower LSM, an LSM ≥ 7...
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