Methods for directed differentiation of pluripotent stem cells to immune cells

作者: Deepika Rajesh , Wen Bo Wang , Sarah A. Burton , Xin Zhang , Maksym A. Vodyanyk

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摘要: Provided herein are methods for the efficient in vitro differentiation of somatic cell-derived pluripotent stem cells to hematopoietic precursor cells, and further into immune various myeloid or lymphoid lineages, particularly T NK dendritic cells. The may be maintained differentiated under defined conditions; thus, use mouse feeder serum is not required certain embodiments

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