Human airway narrowing measured using high resolution computed tomography.

摘要: Exaggerated airway narrowing in response to bronchoconstricting stimuli is a characteristic feature of asthmatic subjects. It unknown whether the site differs subjects from that observed normal Increased wall thickness has been suggested as contributing cause for hyperresponsiveness asthma, based on histologic measurements. We measured and magnitude inhaled methacholine patients with mild moderate asthma using high resolution computed tomography (HRCT). After comparable decrease FEV1, there were no differences or any category size normals. However, results show smaller airways are significantly thickened area does not change after bronchoconstriction whereas it decreases We...