Review article: medical management of the liver transplant recipient - a primer for non-transplant doctors.

摘要: Summary Background Survival 10 years after orthotopic liver transplantation now approaches 65%. Consequently, community doctors must manage the metabolic and neoplastic complications of in an ageing population. Aims To review common sources morbidity mortality long-term recipients, to make evidence-based recommendations regarding their management. Methods Pertinent studies reviews were identified by literature search through PubMed. Where could not be gleaned from literature, expert opinion was obtained syllabi national meetings. Results The two most causes recipients are atherosclerotic vascular disease de novo malignancy. The pathogenesis many begins before transplantation, potentially modifiable. Most complications, however, can directly ascribed immunosuppressive agents. Despite improvements our understanding epidemiology remarkably few randomized-controlled exist define optimal management. Conclusions Orthotopic experience succumb same afflictions old age as non-transplant patients, but with greater frequency at earlier age. surveillance for, treatment of, medical remain based upon rather than medicine.