Benzodiazepines: influence on the developing brain

摘要: Publisher Summary This chapter discusses the influence of benzodiazepine (BDZ) on developing brain. In recent years, neural receptors mediating pharmacological effects many neuroactive drugs are identified. Of particular pertinence to this discussion, specific binding sites for anxiolytic BDZ compounds identified and interaction these with their correlates well anxiolytic, anticonvulsant, sedative muscle-relaxant properties. The full expression drug during development can also depend upon interactions that receptive cells make other neurons maturational state circuitry. Developmental exposure BDZs is associated neural, physiological behavioral alterations in both clinical experimental studies. scope discussion limited presentation results research utero rats. To understand implications fetal brain, it necessary demonstrate a response brain presence drug.