Nephrotoxic amino acid and glutathione S-conjugates: formation and renal activation.
作者： M. W. Anders , Lawrence H. Lash , Adnan A. Elfarra
DOI: 10.1007/978-1-4684-5134-4_43
关键词:
摘要: The mechanisms by which chemicals produce tissue damage include, for example, biotransformation to reactive, electrophilic metabolites, initiation of lipid peroxidation, and formation toxic, reduced oxygen metabolites. liver, because its abundant capacity biotransformation, is frequently the target organ whose toxicity associated with bioactivation. Extrahepatic organs are well known, this may also be
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