Inhibition of ALK, PI3K/MEK and HSP90 in Murine Lung Adenocarcinoma Induced by EML4-ALK Fusion Oncogene

作者: Zhao Chen , Takaaki Sasaki , Xiaohong Tan , Julian Carretero , Takeshi Shimamura

DOI: 10.1158/0008-5472.CAN-10-1671

关键词:

摘要: … (ALK) kinase occur in 3% to 13% of non–small cell lung cancer … for lung cancers driven by an activated EML4-ALK chimeric … In this model, the ALK kinase inhibitor TAE684 produced …

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