Nodular Histiocytic Aggregates in the Greater Omentum of Patients With Ovarian Cancer

摘要: Nodular histiocytic aggregate (NHA) of the omentum is a rare benign proliferative process composed predominantly histiocytes with scattered mesothelial cells. NHA differential diagnosis for neoplasms or metastatic tumors in cancer patients. To further clarify this clinical pitfall issue, authors investigated surgical samples greater from 96 patients gastrointestinal malignancies and 53 gynecologic neoplasms. Visible was identified 3 ovarian (borderline mucinous cystadenoma, low-grade papillary serous cystadenocarcinoma, juvenile granulosa-cell tumor) but none malignancies. Similar lesion also on cell blocks peritoneal washings 1 Grossly, lesions formed small yellow-red nodules omentum, found diffusely surface appendix fallopian tubes 2 Histological study showed that typical changes over an inflammatory background, which may indicate consequence chronic omentum. The predominant infiltration T lymphocytes indicates aggregation be related to activation T-cell immunity. This report has first demonstrated visible malignancies, awareness entity should brought clinicians avoid misdiagnosis.