TERT promoter mutations in telomere biology.
作者： Barbara Heidenreich , Rajiv Kumar
DOI: 10.1016/J.MRREV.2016.11.002
关键词:
摘要: Telomere repeats at chromosomal ends, critical to genome integrity, are maintained through an elaborate network of proteins and pathways. Shelterin complex proteins shield telomeres …
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Bruno Bernardes de Jesus, Maria A Blasco, None, Telomerase at the intersection of cancer and aging Trends in Genetics. ,vol. 29, pp. 513- 520 ,(2013) , 10.1016/J.TIG.2013.06.007
Grzegorz Sarek, Jean-Baptiste Vannier, Stephanie Panier, John H.J. Petrini, Simon J. Boulton, TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding. Molecular Cell. ,vol. 57, pp. 622- 635 ,(2015) , 10.1016/J.MOLCEL.2014.12.024
Jerry W. Shay, Woodring E. Wright, Telomerase therapeutics for cancer: challenges and new directions. Nature Reviews Drug Discovery. ,vol. 5, pp. 577- 584 ,(2006) , 10.1038/NRD2081
Nazneen Rahman, Realizing the promise of cancer predisposition genes Nature. ,vol. 505, pp. 302- 308 ,(2014) , 10.1038/NATURE12981
Feng Wang, Elaine R. Podell, Arthur J. Zaug, Yuting Yang, Paul Baciu, Thomas R. Cech, Ming Lei, The POT1-TPP1 telomere complex is a telomerase processivity factor Nature. ,vol. 445, pp. 506- 510 ,(2007) , 10.1038/NATURE05454
Luis FZ Batista, Matthew F Pech, Franklin L Zhong, Ha Nam Nguyen, Kathleen T Xie, Arthur J Zaug, Sharon M Crary, Jinkuk Choi, Vittorio Sebastiano, Athena Cherry, Neelam Giri, Marius Wernig, Blanche P Alter, Thomas R Cech, Sharon A Savage, Renee A Reijo Pera, Steven E Artandi, None, Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells Nature. ,vol. 474, pp. 399- 402 ,(2011) , 10.1038/NATURE10084
Andrew S Venteicher, Eladio B Abreu, Zhaojing Meng, Kelly E McCann, Rebecca M Terns, Timothy D Veenstra, Michael P Terns, Steven E Artandi, A Human Telomerase Holoenzyme Protein Required for Cajal Body Localization and Telomere Synthesis Science. ,vol. 323, pp. 644- 648 ,(2009) , 10.1126/SCIENCE.1165357
Helena Pópulo, Paula Boaventura, João Vinagre, Rui Batista, Adélia Mendes, Regina Caldas, Joana Pardal, Filomena Azevedo, Mrinalini Honavar, Isabel Guimarães, José Manuel Lopes, Manuel Sobrinho-Simões, Paula Soares, TERT Promoter Mutations in Skin Cancer: The Effects of Sun Exposure and X-Irradiation Journal of Investigative Dermatology. ,vol. 134, pp. 2251- 2257 ,(2014) , 10.1038/JID.2014.163
Paula Martínez, María A Blasco, None, Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins Nature Reviews Cancer. ,vol. 11, pp. 161- 176 ,(2011) , 10.1038/NRC3025
Arthur J Zaug, Elaine R Podell, Thomas R Cech, Mutation in TERT separates processivity from anchor-site function Nature Structural & Molecular Biology. ,vol. 15, pp. 870- 872 ,(2008) , 10.1038/NSMB.1462