Uvaridacols E−H, Highly Oxygenated Antiausterity Agents from Uvaria dac
作者： Suresh Awale , Jun-ya Ueda , Sirivan Athikomkulchai , Dya Fita Dibwe , Sherif Abdelhamed
DOI: 10.1021/NP300596C
关键词:
摘要: Chemical investigation of the stems Uvaria dac yielded four new highly oxygenated cyclohexene derivatives named uvaridacols E− H( 1−4). Their structures were established through NMR and circular dichroism spectroscopic analysis. Uvaridacols E (1), F (2), H (4) displayed weak preferential cytotoxicity against PANC-1 human pancreatic cancer cells under nutrition-deprived conditions in a concentration-dependent manner, without causing toxicity normal nutrient-rich conditions.
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