Heterocyclic Carboxamide Compounds as Steroid Nuclear Receptors Ligands
作者： Brenton T. Flatt , Michael C. Nyman , Tie-Lin Wang , Brett Murphy , Xiao-Hui Gu
DOI:
关键词:
摘要: Heterocyclic carboxamide compounds are described herein as being useful in modulating the activity of steroid nuclear receptors. Pharmaceutical compositions containing compounds, methods using and processes for making also described.
lens.org 参考文章(16)
Herman H. van Stuivenberg, Cornelis G. Kruse, Arnoldus H. J. Herremans, Josephus H. M. Lange, 1H-imidazole derivatives having cb1 agonistic, cb1 partial agonistic or cb1 antagonistic activity ,(2002)
Alexandros Makriyannis, Qian Liu, Pyrazole derivatives as cannabinoid receptor antagonists ,(2000)
Alexandros Makriyannis, Quian Liu, Rajesh Thotapally, Pyrazole analogs acting on cannabinoid receptors ,(2005)
Tsuyoshi Takemoto, Minoru Yamaguchi, Masayuki Morimoto, Masanori Tohnishi, Takashi Furuya, Akira Seo, Shinsuke Fujioka, Substituted anilide derivatives, intermediates thereof, agricultural and horticultural chemicals, and their usage ,(2002)
Marinella Antolini, Andrea Bozzoli, Chiara Ghiron, Gordon Kennedy, Tino Rossi, Antonella Ursini, Analogues of 4,5-bis(3,5-dichlorophenyl)-2-trifluoromethyl-1H-imidazole as potential antibacterial agents Bioorganic & Medicinal Chemistry Letters. ,vol. 9, pp. 1023- 1028 ,(1999) , 10.1016/S0960-894X(99)00112-2
Joong-Youn Shim, William J. Welsh, Etienne Cartier, James L. Edwards, Allyn C. Howlett, Molecular interaction of the antagonist N-(piperidin-1-yl)-5-(4-chlorophenyl)-1- (2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide with the CB1 cannabinoid receptor. Journal of Medicinal Chemistry. ,vol. 45, pp. 1447- 1459 ,(2002) , 10.1021/JM010267O
Noriaki KUDO, Satoru FURUTA, Misa TANIGUCHI, Takeshi ENDO, Kazuo SATO, Synthesis and Herbicidal Activity of 1, 5-Diarylpyrazole Derivatives Chemical & Pharmaceutical Bulletin. ,vol. 47, pp. 857- 868 ,(1999) , 10.1248/CPB.47.857
Taisei Ueda, Izumi Matsuura, Nobutoshi Murakami, Shin-ichi Nagai, Jinsaku Sakakibara, Masafumi Goto, A novel ring transformation of 5-acylaminouracils and 5-acylamino-pyrimidin-4(3H)-ones into imidazoles Tetrahedron Letters. ,vol. 29, pp. 4607- 4610 ,(1988) , 10.1016/S0040-4039(00)80560-2
Ruoxi Lan, Qian Liu, Pusheng Fan, Sonyuan Lin, Susanthi R. Fernando, Deirdre McCallion, Roger Pertwee, Alexandros Makriyannis, Structure-activity relationships of pyrazole derivatives as cannabinoid receptor antagonists. Journal of Medicinal Chemistry. ,vol. 42, pp. 769- 776 ,(1999) , 10.1021/JM980363Y
C. Elisabet Tranberg, Andrea Zickgraf, Brian N. Giunta, Henning Luetjens, Heidi Figler, Lauren J. Murphree, Ruediger Falke, Holger Fleischer, Joel Linden, Peter J. Scammells, Ray. A. Olsson, 2-Amino-3-aroyl-4,5 alkylthiophenes: agonist allosteric enhancers at human A1 adenosine receptors Journal of Medicinal Chemistry. ,vol. 45, pp. 382- 389 ,(2004) , 10.1021/JM010081P