Soy protein, isoflavones, and cardiovascular health: A summary of a statement for professionals from the American Heart Association Nutrition Committee

摘要: This editorial summarizes the recent American Heart Association (AHA) Science Advisory on soy protein and isoflavones (phytoestrogens) published in February 21, 2006, issue of Circulation .1 Soy have gained considerable attention for their potential role improving risk factors cardiovascular disease. scientific advisory report assesses more work its component isoflavones. In 22 randomized trials, isolated with compared milk or other proteins decreased LDL cholesterol concentrations most studies; average effect was approximately 3%. reduction is very small large amount tested these studies, averaging 50 g, half usual total daily intake. No significant effects were evident HDL cholesterol, triglycerides, lipoprotein(a), blood pressure. Among 19 studies isoflavones, lipid nil. not been shown to lessen vasomotor symptoms menopause, results are mixed regarding slowing postmenopausal bone loss. The efficacy safety preventing treating cancer breast, endometrium, prostate established; evidence from clinical trials meager cautionary as regards a possible adverse effect. For this reason, use isoflavone supplements food pills recommended. Thus, earlier research indicating that has clinically important favorable enjoyed confirmation. contrast, many products should be beneficial overall health because high content polyunsaturated fats, fiber, vitamins, minerals low saturated fat. In October 1999, US Food Drug Administration (FDA) approved labeling foods containing protective against coronary heart disease.2 …