Visual cortical function in very low birth weight infants without retinal or cerebral pathology.

摘要: PURPOSE Preterm infants are at high risk of visual and neural developmental deficits. However, the development cortical function in preterm with no retinal or neurologic morbidity has not been well defined. To determine whether premature birth itself alters function, swept parameter evoked potential (sVEP) responses healthy were compared those term infants. METHODS Fifty-two 58 very low weight (VLBW) without significant retinopathy prematurity morbidities enrolled. Recruited VLBW between 26 33 weeks gestational age, weights less than 1500 g. Spatial frequency, contrast, vernier offset sweep VEP tuning functions measured 5 to 7 months' corrected age. Acuity contrast thresholds derived by extrapolating 0 amplitude. These suprathreshold response amplitudes groups. RESULTS showed increased (indicating decreased sensitivity stimuli) reductions for all three measures. changes responsiveness larger <30 ' age subgroup ≥30 weeks' subgroup. CONCLUSIONS had measurable that correlated results suggest absence identifiable abnormalities a effect on is an important factor development.